Table 1.

Clinical characteristics of patients with M-type phospholipase A2 receptor–related membranous nephropathy with or without any HLA risk alleles

Clinical Item	Overall	Any	None
Patients, n	392	44	348
Men	242 (62%)	28 (64%)	214 (62%)
Age, yr	44±16	44±15	44±16
Proteinuria at baseline, g/24 h	4.4±2.8	4.7±2.4	4.3±2.5
Albumin at baseline, g/dl	2.8±0.5	2.8±0.5	2.8±0.5
Serum creatinine at baseline, mg/dl	0.83±0.29	0.85±0.33	0.82±0.28
eGFR at baseline, ml/min per 1.73 m2	102±26	101±29	102±25
Anti-PLA2R antibodies at baseline, U/ml, median (IQR)	81.6 (39.0–168.8)	86.4 (45.9–152.0)	79.2 (38.3–132.0)
eGFR at last follow-up, ml/min per 1.73 m2	90±38	71±46	92±36

HLA risk alleles: DRB1*13:01, DQB1*06:03, DRB1*04:05, or DQB1*03:02. PLA2R, M-type phospholipase A2 receptor; IQR, interquartile range.