Volcano plot of 825 known, nondrug metabolites for participants by baseline eGFR. Fully adjusted included baseline covariates of age, sex, race, BMI Z-score, hypertension, CKD diagnosis (glomerular versus nonglomerular), log base 2 transformed UPCR and eGFR; partially adjusted included all baseline covariates excluding log base 2 transformed UPCR and eGFR.