Figure 14.
Cartoon showing differences in the interaction of LLP2 with T-cell and HIV membranes. a. WT LLP2 binds to the outer headgroup region and thins the T-cell membrane. b. MX2 binds more deeply into the hydrocarbon interior and thins the T-cell membrane to a greater extent. c. WT and MX2 LLP2 only weakly bind to the HIV virion membrane. MSD, membrane spanning domain. Figure from Ref. [15].