Figure 7. A rapid protection induced by intranasal vaccination against other bacteria.

C57BL/6 mice were immunized intranasally (i.n.) with inactivated whole cell (IWC) of (A) P. aeruginosa (IWC(P.a)), n = 5, (B) K. pneumoniae (IWC(K.p)), n = 5, (C) S. aureus (IWC(S.a)), n = 10, or (D) S. pneumoniae (IWC(S.p)), n = 5. On day 7, the immunized mice were challenged intratracheally (i.t.) with the same species. The survival rates were monitored for 7 days. Data are representative of at least two independent experiments.