Fig. 3.

Relationship of disease severity at admission, ICU care and mortality with clinical and laboratory data in younger and older groups. Multivariable logistic regression analysis was done with for five sets of data between non-severe vs. severe at admission, no ICU care vs. ICU care and alive vs. death in (A) younger (age < 65, n = 566) and (B) older (age ≥ 65, n = 717) adults. Five sets included (1) age, gender, number and types of commodities, (2) first and (3) maximum values of WBC, % of neutrophils, monocytes and lymphocytes, albumin, CRP, ferritin, d-dimer, procalcitonin, and (4) first and (5) maximum levels of 12 cytokines (included IL-1β, IL-2, IL-2R, IL-4, IL-5, IL-6, IL-8, IL-10, IL-12, IL-13, Il-17, IFN-γ) . Only significantly increased or decreased values are shown in the figure. Arrows directing up and down indicate increased and decreased levels, respectively, in patients with severe disease at admission, ICU care, and mortality.