Table 6.
Incidence rates of composite outcome of kidney failure and death, stratified by participant’s baseline characteristics
| Subgroup | Number of Patients | Incidence per 1000 pya | 95% CI |
|---|---|---|---|
| Cardiac surgery during index episode of care | |||
| No (comparators) | 6692 | 2.43 | 2.09 to 2.83 |
| No (dialysis-treated AKI) | 1120 | 9.82 | 8.2 to 11.76 |
| Yes (comparators) | 60 | 4.92 | 1.59 to 15.25 |
| Yes (dialysis-treated AKI) | 568 | 9.2 | 6.69 to 12.64 |
| Prior cardiac surgeryb | |||
| No (comparators) | 6212c | 2.45 | 2.10 to 2.86 |
| No (dialysis-treated AKI) | 1461c | 8.63 | 7.23 to 10.29 |
| Yes (comparators) | 76c | 10.84 | 5.17 to 22.74 |
| Yes (dialysis-treated AKI) | 111c | 22.75 | 14.51 to 35.67 |
| Prior malignancyb | |||
| No (comparators) | 5874c | 1.71 | 1.41 to 2.07 |
| No (dialysis-treated AKI) | 1435c | 7.30 | 6.03 to 8.84 |
| Yes (comparators) | 414c | 16.74 | 13.00 to 21.56 |
| Yes (dialysis-treated AKI) | 137c | 45.66 | 33.22 to 62.75 |
| Neonates versus childrend | |||
| Neonates (comparators) | 464 | 1.19 | 0.49 to 2.85 |
| Neonates (dialysis-treated AKI) | 116 | 13.82 | 8.03 to 23.81 |
| Children (comparators) | 6288 | 2.53 | 2.18 to 2.95 |
| Children (dialysis-treated AKI) | 1572 | 9.40 | 7.98 to 11.08 |
Median follow-up time was 9.1 yr for the dialysis-treated AKI cohort and 9.8 yr for the comparator cohort.
Prior cardiac surgery and malignancy were defined by the presence of administrative codes within 5 yr before index hospitalization (or to date of birth if age less than 5 yr at index hospitalization).
Neonates with missing data for prior cardiac surgery and malignancy (580 individuals; 116 in AKI and 464 in comparator cohorts) were excluded from this analysis.
Children included all individuals 29 days to 18 yr at index hospitalization. Neonates were defined as individuals that started dialysis between 0 and 28 days of life. Hospitalized neonates that started dialysis after 28 days of life were defined as children.