Table 3.

Biomarkers Levels Predictive of AKI

Time point	Cut-Off Value	Sensitivity	Specificity	PPV	NPV
Urinary L-FABP (μg/gCr)
Pre-operation	11.3	0.41	0.84	0.52	0.77
Post anesthesia induction	4.8	0.74	0.44	0.36	0.80
2 hours post-AXC	150.5	0.83	0.78	0.61	0.92
Post-operation	129.0	0.68	0.72	0.51	0.84
4 hours post-operation	93.9	0.74	0.78	0.59	0.88
POD 2	19.1	0.90	0.56	0.46	0.93
Urinary NGAL (mg/gCr)
Pre-operation	8.09	0.82	0.33	0.34	0.81
Post anesthesia induction	7.51	0.53	0.80	0.53	0.80
2 hours post-AXC	48.67	0.72	0.89	0.73	0.88
Post-operation	16.58	0.84	0.56	0.45	0.89
4 hours post-operation	41.73	0.68	0.80	0.59	0.86
POD 2	35.11	0.67	0.82	0.61	0.85
Urinary albumin (mg/gCr)
Pre-operation	22.7	0.59	0.88	0.68	0.84
Post anesthesia induction	42.8	0.68	0.67	0.47	0.83
2 hours post-AXC	607.2	0.78	0.73	0.55	0.89
Post-operation	101.4	0.74	0.65	0.47	0.86
4 hours post-operation	41.7	0.90	0.62	0.50	0.94
POD 2	25.5	0.83	0.67	0.52	0.90

Abbreviations: AKI, acute kidney injury; PPV, positive predictive value; NPV, negative predictive value; L-FABP, liver-type fatty acid binding protein; AXC, aorta cross clamping; POD, post-operative day; NGAL, Neutrophil gelatinase-associated lipocalin.