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. 2021 Jul 23;21(5):608–621. doi: 10.1038/s41397-021-00238-4

Table 2.

Demographic and clinical characteristic of rheumatoid arthritis patients with poor and good MTX response.

Poor MTX response Good MTX response p
Median (range) Median (range)
Age 61 (25–88) 56 (22–89) 0.008
Female/male 97 (89%)/11 45 (90%)/5 >0.99a
Disease duration (years) 12 (0–48) 7.5 (0.5–30) 0.028
ESR (mm/h) 39 (0–160) 15 (1–86) <0.0001
CRP (mg/l) 19.50 (1.3–89) 7 (0–104) <0.0001
DAS28 5.45 (1.99–7.9) 2.65 (0.97–5.95) <0.0001
n (%) n (%) OR (95% CI) pa
Larsen ≥3 69 (60%) 24 (43%) 2 (1.05–3.71) 0.049
RF positive 74 46 3.3 (1.6–7.05) 0.002
Anti-CCP positive 82 75 1.7 (0.7–4.15) 0.32

aFisher test.