Table 8.

Potential bivalent genes critical for islet maturation

Gene	Gene name	Bivalency		logFC	FDR
		2-week	10-week
Reg3g	Regenerating islet-derived protein 3 gamma	Y	N	5.88	1.19E-07
Ccl5	C-C motif chemokine ligand 5	Y	N	3.33	4.04E-07
Chst5	Carbohydrate sulfotransferase 5	Y	N	2.75	4.19E-07
Fgf21	Fibroblast growth factor 21	Y	N	2.98	1.65E-05
Tp63	Tumor protein p63	Y	N	4.56	1.39E-04
Slco4c1	Solute carrier organic anion transporter family, member 4C1	Y	N	2.64	2.52E-04
Zbp1	Z-DNA binding protein 1	Y	N	3.49	3.75E-04
Sh2d4b	SH2 domain containing 4B	Y	N	2.15	2.15E-03
Gzma	Granzyme A	Y	N	2.56	1.08E-02
Cxcr2	C-X-C motif chemokine receptor 2	Y	N	2.22	1.77E-02
Bpifa2f	BPI fold containing family A, member 2F	Y	N	2.16	2.09E-02
Kmo	Kynurenine 3-monooxygenase	Y	N	2.48	2.50E-02
Ankrd34a	Ankyrin repeat domain 34A	Y	N	1.15	2.64E-02
Tnn	Tenascin N	Y	N	3.00	3.95E-02
Serpina11	Serpin family A member 11	Y	N	1.54	4.10E-02
Mxd3	Max dimerization protein 3	N	Y	-2.16	2.40E-07
Gdpd2	Glycerophosphodiester phosphodiesterase domain containing 2	N	Y	-3.11	2.01E-05
Camp	Cathelicidin antimicrobial peptide	N	Y	-5.50	2.71E-05
Rtkn2	Rhotekin 2	N	Y	-1.83	5.26E-05
Fam71f1	Family with sequence similarity 71, member F1	N	Y	-2.78	6.44E-05
Slc26a3	Solute carrier family 26 member 3	N	Y	-2.78	7.31E-04
Ebf4	EBF family member 4	N	Y	-1.68	8.02E-04
LOC303566	Homologous recombination factor with OB-fold	N	Y	-1.54	1.43E-03
Dmgdh	Dimethylglycine dehydrogenase	N	Y	-3.37	1.61E-03
Tssk4	Testis-specific serine kinase 4	N	Y	-1.81	2.43E-03
Fabp7	Fatty acid binding protein 7	N	Y	-2.90	2.71E-03
Bglap	Bone gamma-carboxyglutamate protein	N	Y	-2.77	4.62E-03
Vnn3	Vanin 3	N	Y	-1.96	6.28E-03
Chad	Chondroadherin	N	Y	-1.59	6.29E-03
Sfta2	Surfactant associated 2	N	Y	-2.45	8.01E-03
Folh1	Folate hydrolase 1	N	Y	-1.87	9.84E-03
Hoxd10	Homeo box D10	N	Y	-2.22	1.41E-02
Cdh16	Cadherin 16	N	Y	-1.45	2.38E-02
Tsga10ip	Testis-specific 10 interacting protein	N	Y	-1.33	4.57E-02

Abbreviations: FDR, false discovery rate; N, no; Y, yes.