Table 2.
Associations of Risk factors with Outcome of Neutropenia
Unadjusted Hazard Ratio (HR) |
95% Confidence Interval (CI) |
Adjusted HR | 95% CI | ||
---|---|---|---|---|---|
Lower Baseline WBC per unit/mm3 | 1.10 | 1.01-1.21 | 1.12 | 1.11-1.24 | |
Pre-Transplant Left Ventricular Assist Device | 1.63 | 1.01-2.66 | 1.63 | 1.00-2.66 | |
Baseline eGFR ≤ 60 mL/min/1.73m2 | 1.56 | 1.02-2.39 | Not in adjusted model | ||
High Risk CMV Serostatus (D+/R−) | 1.87 | 1.21-2.88 | 1.86 | 1.19-2.88 | |
Length of Transplant Hospital Stay (per week) | 1.05 | 1.01-1.10 | Not in adjusted model | ||
Valganciclovir at Time of Hospital Discharge | 2.14 | 1.35-3.38 | Not in adjusted model | ||
Previous CMV infection – time dependent | 8.40 | 4.52-15.6 | 4.07 | 3.92-13.7 |
Abbreviations: WBC: white blood cell; eGFR: estimated glomerular filtration rate; CMV: cytomegalovirus, D: donor, R: recipient,