Table 1:
Clinical Characteristics and Risk Factors of Children with Peripancreatic Vascular Complications
| Patient | Sex | Age at first AP | Age at thrombosis | Current diagnosis | Severity of AP at thrombosis | Location of thrombus | Diagnostic Imaging | Risk factors | Genetic variants |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Female | 3 years | 13 years | ARP | Mild | Splenic vein | MRI/MRCP | Genetic | PRSS1 R122H |
| 2 | Female | 12 years | 14 years | CP | Moderately severe or severe | Portal vein | US with doppler | Genetic Obstructive (duct obstruction with large stones within the pancreatic duct) | PRSS1 R122C and c.40 +13C>T, CFTR (TG) 11–5T/ (TG) 11–7T |
| 3 | Female | 4 years | 9 years | ARP | Moderately severe or severe | Splenic vein and portal vein | CT scan | Idiopathic | Unknown |
| 4 | Female | 10 years | 15 years | CP | Moderately severe or severe | Splenic vein | CT scan | Hypertriglyceridemia | PPARG |
| 5 | Female | 3 years | 6 years | CP | Moderately severe or severe | Left gastric artery | CT scan | Pancreas divisum | Unknown |
MRCP: Magnetic Resonance Cholangiopancreatography; US: Ultrasound; CT scan: Computerized Tomography scan; ARP: acute recurrent pancreatitis; CP: chronic pancreatitis