Table 2.

Basic clinical and neuroimaging characteristics of ischemic stroke patients with and without intracranial hemorrhage after rtPA treatment.

	Without ICH (N = 32)	With ICH (N = 9)	p value*
NIHSS on admission			0.221
Min–Max	1.00–18.00	2.00–17.00
Mean	6.12	7.78
Median (Q1,Q3)	5.00 (3.00, 6.25)	7.00 (4.00, 11.00)
NIHSS on discharge			0.458
Min–Max	0.00–15.00	0.00–7.00
Mean	1.44	2.22
Median (Q1,Q3)	0.50 (0.00, 1.25)	1.00 (0.00, 3.00)
Age			0.344
Min–Max	19.00–94.00	51.00–91.00
Mean	64.56	72.56
Median (Q1,Q3)	67.00 (52.00, 80.25)	71.00 (59.00, 84.00)
Sex, male	11 (34.4%)	6 (66.7%)	0.128
Hypertension	23 (71.9%)	8 (88.9%)	0.410
Diabetes	8 (25.0%)	3 (33.3%)	0.680
Hiperlipidemia	20 (62.5%)	8 (88.9%)	0.228
Atrial Fibrillation	7 (21.9%)	0 (0.0%)	0.315
Active smoking	10 (31.2%)	3 (33.3%)	< 1.000
Baseline infarct volume [ml]			0.050
Min–Max	0.00–64.02	1.14–55.57
Mean	11.88	23.87
Median (Q1,Q3)	2.63 (0.00, 17.02)	16.02 (10.36, 36.91)

ICH—intracranial hemorrhage, NIHSS—National Institute of Health Stroke Scale; Q1—the first quartile; Q3—the third quartile; *Mann–Whitney U test was applied for comparison of quantitative data, whereas Fisher’s exact test was used to compare binomial data; p value equal or less than 0.05 was considered statistically significant.