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. 2021 Sep 21;11:18750. doi: 10.1038/s41598-021-98407-9

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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The relation of the fibrous scar lesion and muscle regeneration in wound healing in the abdominal muscle wall. (A) The representative lesions of the fibrous scarring and muscle regeneration stained by MT and myoglobin staining using serial sections; The lesion in the upper panel was from the control group on day 21, and the lesion in the lower panel was from the Pro-Hyp group on day 21. The lower panel shows the stumped muscle (M), from which regenerated muscle cells migrate into the granulation tissue. Bars = 200 µm. (B) The relation of fibrosis area (%) and myoglobin positive area (%) in the granulation tissue obtained from both groups on day 21.