Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Sep 21;4:1109. doi: 10.1038/s42003-021-02630-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 5 — Representative images and quantification of: a cholesterol crystal clefts, indicated by arrows (H&E staining); b macrophages (F4/80 staining); c α-smooth muscle cells (α-SMA staining); d collagen (Masson’s Trichrome staining) in atherosclerotic lesions from aortic roots of Pcyox1^+/+/Apoe^−/− (n = 8) and Pcyox1^−/−/Apoe^−/− (n = 11) mice fed a HFD for 8 weeks. Shown on the right are the results of the morphometric analysis for the different stainings, expressed either as absolute positive areas within the intima or as percentage of plaque that stained for each component. e Calculation of vulnerability plaque index. Data are presented as circle plot, with each circle representing an individual sample and bars showing the mean value ± SEM (a) or median with interquartile range (b–e). Statistical significance was calculated by Student’s t test (a) or Mann–Whitney test (b–e).