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. 2021 Sep 21;6:76. doi: 10.1038/s41525-021-00239-z

Fig. 5. Novel mutations predicted to confer drug sensitivity.

Fig. 5

a List of top 1% mutations predicted to confer sensitivity to a specific agent across tumor types. Linear model p-values all <0.0001. The rank is based on the normalized weighting of the model with each model. b Differences in TARGETS scores across 32 cancer types for Linsitinib. c Differences in TARGETS scores across 32 cancer types for Elesclomol. A lower TARGETS score indicates predicted sensitivity. Boxplot center line = median; box limits = upper and lower quartiles; whiskers = 1.5× interquartile range.