Fig. 2. Screening of HNPs for histone affinity.

a Schematic of synthetic HNPs synthesized by free-radical copolymerization of functional monomers. b TEM image of HNPs. The experiment was repeated three times. c Affinity of HNPs for histones. QCM sensor cells were functionalized with histones. After blocking with BSA, each type of HNPs was added and their binding amount was measured. d Affinity of HNP4 for the purified histone subtypes. QCM sensor cells were functionalized with the purified histone subtypes. After blocking with BSA, HNP4 was added and its binding amount was measured. Data represent the means of independent duplicate measurements.