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. 2021 Sep 3;24(9):103081. doi: 10.1016/j.isci.2021.103081

Figure 4.

Figure 4

Gene evolution among 14 pig breeds

(A) gene families among three miniature pig breeds.

(B) phylogenetic tree of 14 pig breeds (also see Figure S12).

(C) positively selected site of Ossabaw LEPR gene. ①, ②, ③ represent possible splice sites of exon 12 (also see Figures S13 and S14).

(D) gene network of LEPR. This network was referenced from the STRING database (https://string-db.org/). The colored circles represent the corresponding biological processes to which these genes are related, and the thickness of lines represents the strength of gene interaction.

(E) Heatmap of gene expression (FPKM, Fragments Per Kilobase of exon model per Million mapped fragments) for LEPR network genes, from an Ossabaw diet experiment (Walker et al., 2019), WD (Western style diet) and HHD (Heart Healthy style diet) group.