Table 2.

VEGF level in DFU swab Base on Intervention.

Intervention	A-PRF + AH (n = 10)	A-PRF (n = 10)	control (n = 10)	p-value
Before∗	232,8 (SD 125,7)	185,7(SD 100,8)	183,7 (SD 127,2)	0,568
After day-3∗	320,6 (SD 165,8)	180,4 (SD 87,4)	144,8 (SD 87,7)	0,007
After day-7∗	544,5 (SD 266,8)	272,8 (SD 97,7)	167,4 (SD 98,8)	<0,001

Post-hoc anova anova:

A-PRF + HA group increase significantly compare with control on day -3 (p = 0,008) and day -7 (p < 0,001).

A-PRF + HA group increase significantly compare with A-PRF on day-3 (p = 0,042) and day-7 (p = 0,005).

A-PRF group increase not significantly compare with control on day-3 (p = 1.000) and day -7 (p = 0,559).

^∗Data mean (SD), anova tes.