FIGURE 2.
GABA levels (nM ± SEM) in the IPN of female (control n = 6; nicotine-treated n = 6) and male (control n = 6; nicotine-treated n = 6) rats. The top panels reflect raw dialysate levels and the bottom panel reflects percentchange in nicotine-treated female and male rats relative to their respective controls. Each point reflects a 20-min sampling period during baseline and then following mecamylamine administration to precipitate withdrawal (shaded area). Asterisks (*) denote a difference from controls, daggers (†) denote a difference from baseline, and pound signs (#) denote a sex difference between female and male rats (p ≤ 0.05)
