Table 3.
Bleeding events and ischaemic events during follow-up
| Bleeding endpoint | Cumulative (n = 524) | T1 visit (n = 524) | T2 visit b (n = 456) | T3 visit b (n = 420) |
|---|---|---|---|---|
| Any bleeding | 254 (48.5) | 147 (28.1) | 135 (29.6) | 82 (19.5) |
| Most severe bleeding | ||||
| – BARC type 1 | 162 (30.9) | 102 (19.5) | 105 (23.0) | 54 (12.9) |
| – BARC type 2 | 63 (12.0) | 34 (6.5) | 19 (4.2) | 19 (4.5) |
| – BARC type 3 | 29 (5.5) | 11 (2.1) | 11 (2.4) | 9 (2.1) |
| Total number of bleeding events a | 442 | 188 | 159 | 95 |
| – BARC type 1 | 332 (75.1) | 139 (73.9) | 126 (79.2) | 67 (70.5) |
| – BARC type 2 | 75 (16.9) | 36 (19.1) | 20 (12.6) | 19 (20.0) |
| – BARC type 3 | 35 (7.9) | 13 (6.9) | 13 (8.2) | 9 (9.5) |
| Ischaemic event |
Cohort (n = 524) |
|||
| No ischaemic events | 416 (79.2) | |||
| Major adverse cardiovascular event (myocardial infarction, stroke or all-cause death) | 69 (13.2) | |||
| Myocardial infarction | 36 (6.9) | |||
| Stent thrombosis | 8 (1.5) | |||
| Stroke | 13 (2.5) | |||
| Death, all-cause | 23 (4.4) | |||
| – Confirmed cardiovascular death c | 6 (1.1) | |||
| – Death (non-cardiovascular, unknown) | 17 (3.2) | |||
| Coronary revascularisation | 37 (7.1) | |||
| PAD with revascularisation | 17 (3.2) | |||
| Venous thromboembolism | 3 (0.6) | |||
BARC Bleeding Academic Research Consortium, PAD peripheral artery disease
a In patients reporting any bleeding symptoms (one patient can report more than one bleeding event at the same visit)
b Bleeding events since last study visit
c Confirmed cardiovascular death is defined as death due to acute myocardial infarction, death due to stroke, or in-hospital cardiac arrest