Table 3.

2D matching features. Number and percentage of matching stable features obtained with 2D contour-focused segmentation, as well as number and percentage of matching stable features with good (ICC ≥ 0.75) overall interobserver reliability across different imaging modalities and MRI sequences, grouped according to feature class and image type. GLCM, gray-level cooccurrence matrix; GLDM, gray-level dependence matrix; GLRLM, gray-level run length matrix; GLSZM, gray-level size zone matrix; ICC, intraclass correlation coefficient; LoG, Laplacian of Gaussian

2D	Feature class	Image type	Total features (n)	Matching features (n)	Matching features (%)	ICC ≥ 0.75 (n)	ICC ≥ 0.75 (%)
CT + MRI (T1w + T2w)	First order	LoG	72	61	84.72	4	6.56
		Original	18	15	83.33	0	0
		Wavelet	72	45	62.50	3	6.67
	GLCM	LoG	88	74	84.09	2	2.70
		Original	22	11	50.00	0	0
		Wavelet	88	55	62.50	2	3.64
	GLDM	LoG	56	41	73.21	4	9.76
		Original	14	7	50.00	0	0
		Wavelet	56	29	51.79	6	20.69
	GLRLM	LoG	64	48	75.00	1	2.08
		Original	16	10	62.50	1	10.00
		Wavelet	64	36	56.25	7	19.44
	GLSZM	LoG	64	40	62.50	1	2.50
		Original	16	7	43.75	0	0
		Wavelet	64	28	43.75	3	10.71
	Shape	Original	9	8	88.89	4	50.00
	Overall		783	515	65.77	38	7.38
MRI (T1w + T2w)	First order	LoG	72	63	87.50	8	12.70
		Original	18	15	83.33	0	0
		Wavelet	72	50	69.44	6	12.00
	GLCM	LoG	88	80	90.91	2	2.50
		Original	22	17	77.27	1	5.88
		Wavelet	88	65	73.86	2	3.08
	GLDM	LoG	56	43	76.79	2	4.65
		Original	14	9	64.29	1	11.11
		Wavelet	56	37	66.07	6	16.22
	GLRLM	LoG	64	51	79.69	1	1.96
		Original	16	12	75.00	2	16.67
		Wavelet	64	46	71.88	2	4.35
	GLSZM	LoG	64	50	78.13	1	2.00
		Original	16	8	50.00	0	0
		Wavelet	64	40	62.50	2	5.00
	Shape	Original	9	9	100.00	4	44.44
	Overall		783	595	75.99	40	6.72