TABLE 2.
lncRNAs participate in the regulation of ferroptosis.
| lncRNA | Target | Regulatory direction for target | Effect to ferroptosis (references) |
| ZFAS1 | SLC38A1 | activation | enhance ferroptosis (Yang Y.N. et al., 2020) |
| PVT1 | TFR | inhibition | block iron intake (Xu et al., 2018) |
| H19 | MAPK/ERK signaling | regulation | modulate ROS production (Ding et al., 2018) |
| GABPB1AS1 | peroxiredoxin-5 peroxidase | inhibition | decrease antioxidant capacity (Qi et al., 2019) |
| OIP5-AS1 | miR-128-3p/SLC7A11 signaling | sponge | inhibit ferroptosis (Zhang Y. et al., 2021) |
| NEAT1 | ACSL4 | regulation | regulate ferroptosis and ferroptosis sensitivity (Wu and Liu, 2021) |
| LINC00618 | lymphoid-specific helicase (LSH) | attenuate LSH to recruit to the promoter regions of SLC7A11 | increase ROS and iron, accelerate ferroptosis (Wang Z. et al., 2021) |
| MT1DP | miR-365a-3p/NRF2 axis | stabilize miR-365a-3p to modulate NRF2 expression | increase intracellular ferrous iron (Gai et al., 2020) |
| LINC00336 | ELAVL1 | binding | inhibit ferroptosis (Wang M. et al., 2019) |
| P53RRA | G3BP1 | binding | cytosolic P53RRA-G3BP1 interaction displaces p53 from a G3BP1 complex, induce ferroptosis (Mao et al., 2018) |