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. 2021 Sep 17;14:5807–5824. doi: 10.2147/IJGM.S325467

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© 2021 Shen and Liu.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

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The correlation between immune checkpoints and immune infiltration (TIMER). (A) The correlation between ICOSLG expression and the abundance of CD8+ T cells, CD4+ T cells, Macrophage, Neutrophils and Dendritic cells. (B) The correlation between CD70 expression and the abundance of CD8+ T cells, CD4+ T cells, Macrophage, Neutrophils and Dendritic cells. (C) the correlation between SCNA of ICOSLG and immune cell infiltration. (D) the correlation between SCNA of CD70 and immune cell infiltration. (E, F). The correlation between immune checkpoints and the expression of immune biomarkers in STAD. Red color represents positive correlation, blue color represents negative correlation. *P < 0.05, **P < 0.01, ***P < 0.001.

Abbreviation: SCNA, somatic copy number alterations.