Table 2.
Baseline characteristics of study participants (mean ± SD).
| Characteristic | Lean group N = 25 | Obese group N = 25 | p-Value |
|---|---|---|---|
| Gender (Male:Female) | 11:14 | 13:12 | |
| Age | 28 ± 3 | 31 ± 10 | 0.501 |
| BMI | 22.53 ± 2.04 | 40.61 ± 8.40 | <0.001 |
| SBP (mmHg) | 123 ± 5 | 128 ± 6 | 0.116 |
| DBP (mmHg) | 70 ± 5 | 73 ± 6 | 0.224 |
| Fasting glucose (mmol/L) | 4.82 ± 0.75 | 6.43 ± 2.75 | 0.023 |
| Triglyceride (mmol/L) | 1.00 ± 0.37 | 2.15 ± 1.90 | 0.005 |
| Total cholesterol (mmol/L) | 4.40 ± 0.47 | 4.81 ± 1.04 | 0.160 |
| Serum creatinine (mmol/L) | 62.25 ± 15.06 | 59.87 ± 16.53 | 0.221 |
| Cystatin C (mg/L) | 0.73 ± 0.17 | 1.07 ± 0.29 | 0.067 |
| Serum uric acid (mmol/L) | 354.1 ± 61.9 | 459.0 ± 122.8 | <0.001 |
| Angiotensin I (ng/ml/h) | 0.63 ± 0.22 | 4.65 ± 3.98 | 0.007 |
| Angiotensin II (pg/ml) | 33.36 ± 7.81 | 74.83 ± 26.88 | <0.001 |
| Renin (ng/ml/h) | 0.34 ± 0.24 | 3.14 ± 2.90 | 0.024 |
| ACR(mg/g) | 14.73 ± 4.10 | 58.14 ± 38.36 | 0.154 |
Group comparison by Student t-test for independent samples. SBP, systolic blood pressure; DBP, diastolic blood pressure; BMI, body mass index; ACR, albumin-to-creatinine ratio. A P-value of < 0.05 was considered statistically significant.