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. 2021 Sep 8;8:729030. doi: 10.3389/fmed.2021.729030

Table 3.

Comparison of predictive efficiency of varied prognostic models.

Models 28 day prediction
AUROC 95%CI Z value P value Sensitivity Specificity Cut-off
TATIM 0.828 0.738–0.892 7.620 <0.001 95.5 60.1 −1.855
CLIF-C ACLF 0.797 0.706–0.870 6.441 <0.001 100.0 50.6 36
COSSH ACLF 0.796 0.705–0.869 7.293 <0.001 100.0 40.5 5
SOFA 0.729 0.635–0.811 4.091 <0.001 58.33 78.3 7
iMELD 0.725 0.628–0.809 4.113 <0.001 62.5 79.8 4
MELD 0.661 0.561–0.752 2.645 <0.001 54.2 84.2 25
Child-Pugh 0.547 0.446–0.646 1.280 0.201 66.7 53.6 10

CLIF-C ACLF, ACLF model of European Association for the Study of Chronic Liver Failure; SOFA, chronic liver failure-sequential organ failure assessment; MELD, Model for End-stage Liver Disease; SOFA, sequential organ failure assessment; COSSH ACLF, ACLF model of Chinese Group on the Study of Severe Hepatitis B.