Table 2.

TWAS analysis in the four tissues.

Gene	GWAS P	Chr : Start-End	Tissue	Brain Z (PIP)	Blood Z (PIP)	Lung Z (PIP)	Skin Z (PIP)
SLC30A9	2.07×10-12	4:41992489-42092474	Brain, blood, lung	-6.08 (0.313)	-1.83 (<0.01)	3.72 (<0.01)
NDUFA2	2.25×10-6	5:140018325-140027370	Brain, blood, skin	6.27 (0.941)	4.28 (0.011)		-2.87 (<0.01)
FCHSD1	5.99×10-8	5:141018869-141030986	Brain, lung, blood	5.64 (0.807)	1.86 (<0.01)	2.42 (<0.01)
PCDHA7	7.62×10-9	5:140213969-140391929	Lung, brain, skin	-5.02 (0.150)		-5.18 (0.317)	-3.65 (0.013)
WDR55	2.24×10-6	5:140044261-140053709	Skin, blood, lung, brain	-1.56 (<0.01)	-4.65 (0.026)	-1.86 (<0.01)	-4.69 (0.059)
IK	2.25×10-6	5:140026643-140042064	Blood, skin, lung, brain	-3.67 (<0.01)	4.52 (0.034)	-3.7 (<0.01)	-3.37 (<0.01)
TMCO6	2.25×10-6	5:140019012-140024993	Blood, skin, lung, brain	-1.61 (<0.01)	-4.27 (<0.01)	-3.41 (<0.01)	-2.98 (<0.01)
ZMAT2	2.51×10-6	5:140078265-140086248	Lung, blood, skin, brain	-3.5 (<0.01)	2.73 (<0.01)	-2.2 (<0.01)	-2.98 (<0.01)
ZNF391	3.07×10-10	6:27342394-27371683	Brain, skin, blood, lung	2.54 (0.268)	3.83 (<0.01)	-3.86 (<0.01)	3.13 (<0.01)
ESR2	1.42×10-9	14:64550950-64804830	Lung, skin, blood		-5.09 (0.256)	-3.96 (0.243)	-5.58 (0.998)
MTHFD1	5.20×10-9	14:64854749-64926722	Lung, blood, skin		-3.05 (<0.01)	-3.18 (0.018)	-3.32 (<0.01)
MEI1	9.03×10-10	22:42095503-42195460	Brain, skin, lung, blood	6.52 (0.424)	5.88 (<0.01)	5.95 (<0.01)	6.37 (0.042)
XPNPEP3	2.65×10-8	22:41253081-41363838	Blood, skin, lung, brain	3.97 (<0.01)	4.87 (0.045)	5.11 (0.017)	5.42 (0.035)
CCDC134	2.14×10-9	22:42196683-42222303	Brain, lung, blood, skin	3.91 (<0.01)	1.63 (<0.01)	2.49 (<0.01)	-1.82 (<0.01)
DESI1	1.10×10-9	22:41994032-42017100	Lung, skin, brain, blood	2.35 (<0.01)	1.51 (<0.01)	2.34 (<0.01)	2.91 (<0.01)