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. 2021 Sep 8;8:731593. doi: 10.3389/fmed.2021.731593

Table 2.

Univariate analysis of associated factors for adverse reactions in women and men.

Variables n Adverse reactions in women ( n = 1107) n Adverse reactions in men ( n = 290)
After one vaccination After both vaccination After one vaccination After both vaccination
No. Frequency (%) No. Frequency (%) P No. Frequency (%) No. Frequency (%) P
Age (years) 0.237 0.475
18-29 346 48 13.9 29 8.4 71 8 11.3 4 5.6
30-39 482 81 16.8 42 8.7 77 8 10.4 7 9.1
40-49 231 25 10.8 17 7.4 97 9 9.3 2 2.1
50-60 48 11 22.9 3 6.3 45 5 11.1 1 2.2
Total service time (years) 0.863 0.924
<5 373 58 15.5 29 7.8 106 10 9.4 5 4.7
≥5 734 107 14.6 62 8.4 184 20 10.9 9 4.9
Education level 0.186 0.194
Junior College and below 359 50 13.9 21 5.8 87 6 6.9 1 1.1
Undergraduate 690 104 15.1 63 9.1 124 15 12.1 7 5.6
Graduate 58 11 19.0 7 12.1 79 9 11.4 6 7.6
Position 0.158 0.605
Health professionals 881 136 15.4 78 8.9 200 22 11.0 11 5.5
Administrative support staff 226 29 12.8 13 5.8 90 8 8.9 3 3.3
Professional titles 0.813 0.406
Internship or primary 466 73 15.7 37 7.9 109 8 7.3 6 6.0
Medium or higher 641 92 14.4 54 8.4 181 22 12.2 8 4.4
Body mass index (kg/m 2 ) 0.148 0.031
<24 876 139 15.9 68 7.8 126 10 7.9 2 1.6
≥24 231 26 11.3 23 10.0 164 20 12.2 12 7.3
Underlying disease 0.186 0.032
No 1020 148 14.5 81 7.9 233 20 8.6 9 3.9
Yes 87 17 19.5 10 11.5 57 10 17.5 5 8.8
Take medication before vaccination 0.052 0.682
No 1059 153 14.4 85 8.0 258 28 10.9 12 4.7
Yes 48 12 25.0 6 12.5 32 2 6.3 2 6.3
Adverse reactions to other vaccines <0.001 <0.001
No 1046 140 13.4 81 7.7 277 28 10.1 8 2.9
Yes 61 25 41.0 10 16.4 13 2 15.4 6 46.2
Worry about adverse reactions <0.001 <0.001
No 472 41 8.7 24 5.1 171 6 3.5 7 4.1
Yes 635 124 19.5 67 10.6 119 24 20.2 7 5.9
Knowledge of inactivated vaccine being used in the hospital 0.015 0.266
Inactivated vaccine 874 138 15.8 80 9.2 232 26 11.2 13 5.6
Others 233 27 11.6 11 4.7 58 4 6.9 1 1.7
Take vaccine for the family proactively <0.001 0.274
Yes 782 98 12.5 52 6.6 234 24 10.3 9 3.8
No/Not sure 325 67 20.6 39 12.0 56 6 10.7 5 8.9
Get influenza vaccination 0.021 0.913
No 802 114 14.2 56 7 217 23 10.6 11 5.1
Yes 305 51 16.7 35 11.5 73 7 9.6 3 4.1
Allergic reaction 0.008 0.252
No 1038 146 14.1 85 8.2 275 28 10.2 12 4.4
Yes 69 19 27.5 6 8.7 15 2 13.3 2 13.3
Health status before vaccination <0.001 0.795
Good 1009 134 13.3 78 7.7 279 29 10.4 13 4.7
General /Worse 98 31 31.6 13 13.3 11 1 9.1 1 9.1
Sleep quality before vaccination <0.001 0.248
Good 833 98 11.8 58 7.0 235 21 8.9 11 4.7
General /Worse 274 67 24.5 33 12.0 55 9 16.4 3 5.5

Statistically significant values at p < 0.05 are shown in bold.