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. 2021 Sep 8;12:673703. doi: 10.3389/fneur.2021.673703

Table 2.

Demographics, characteristics, treatment details, and clinical outcomes of acute ischemic stroke patients in the COVID-19 period in comparison to the pre-COVID-19 period.

COVID-19 pre-COVID-19 t/Z/χ2 P value
(n = 56) (n = 113)
Female, n (%) 23 (41.1) 46 (40.7) 0.002 0.964
Age (years), mean ± SD 71 ± 13 68 ± 14 1.307 0.193
Urban resident, n (%) 21 (37.5) 45 (39.8) 0.085 0.771
LKN to hospital arrival(min), IQR 242.5 (181,599) 359 (185,1377) 1.518 0.129
Arrival mode: EMS, n (%) 21 (37.5) 27 (23.9) 3.409 0.065
Length of stay (d), IQR 10.5 (5.75,15) 11 (6,13) 0.884 0.377
Denial of medical services, n (%) 14 (25.0) 28 (24.8) 0.001 0.975
NIHSS at presentation, mean ± SD 9 ± 8 9 ± 8 0.148 0.882
Intravenous thrombolysis, n (%) 11 (19.6) 30 (26.5) 0.972 0.324
Door-to-needle (min), mean ± SD 52.45 ± 26.14 43.13 ± 34.27 0.822 0.416
Endovascular thrombectomy, n (%) 11 (19.6) 16 (14.2) 0.839 0.360
Door-to-puncture(min), mean ± SD 109.18 ± 71.39 270.50 ± 161.51 3.526 0.002
mRS at 90 days ≥ 3, n (%) 10 (17.9) 26 (23.0) 0.593 0.441
Deaths, n (%) 2 (3.6) 4 (3.5) 0.000 1.000

COVID-19, coronavirus disease 2019; LKN, last known normal; EMS, emergency medical services; SD, standard deviation; IQR, interquartile range; Denial of medical services indicates the patient had a refusal of medical care recommended by medical personnel; NIHSS, National Institutes of Health Stroke Scale; mRS, modified Rankin Scale.