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. 2021 Sep 8;11:682917. doi: 10.3389/fonc.2021.682917

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Copyright © 2021 Liu, Zhang, Xu, Liu, Sun, Che and He

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Determination of genes differently expressed between normal ovarian tissue and ovarian cancer tissue. (A) Flow diagram of current bioinformatics research: a combination of RNA-Seq analysis and TCGA database. (B) Volcano plot of all genes differentially expressed between normal ovarian tissue (n = 3) and ovarian cancer tissue (n = 3), at a significance thresholds of |log2(Fold Change)| > 1, Padj<0.05. (C) Venn diagram of the results of the analyses of RNA-Seq and differently expressed genes (DEGs) in TCGA and GTEx. (D, E) GO (D) and KEGG (E) enrichment pathway analysis involving intersection DEGs.