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. 2021 Sep 8;11:682917. doi: 10.3389/fonc.2021.682917

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Copyright © 2021 Liu, Zhang, Xu, Liu, Sun, Che and He

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Apigenin inhibits ovarian cancer induced by histamine through attenuating PI3K/AKT/mTOR pathway. (A) Western blot analysis of PI3K, Akt and mTOR expression level of differently-treated OVCAR-3 cells. (B) Western blot analysis of p-PI3K, p-Akt and p-mTOR expression level. *P < 0.05 (Compared to untreated OVCAR-3 cell group); ^# P < 0.05 (compared with the HA-treated group).