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. 2021 Sep 8;12:729062. doi: 10.3389/fphar.2021.729062

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Copyright © 2021 Zhang, Guan, Zhang, Li, Xu, Gong, Chen and Lu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Nqo1-AS1 and Nqo1 mRNA expressions in lung tissues of mice exposed to cigarette smoke (CS) for 1 week (A), 1 month (B) and 3 months (C). The expression levels of Nqo1-AS1 and Nqo1 mRNA in lung tissues of mice exposed to CS and those of control animals were measured by qRT-PCR. Expression level of Nqo1-AS1 was positively correlated with Nqo1 mRNA expression in lung tissues of mice with and without CS exposure. n = 6/group for (A). n = 7/group for (B) and (C) (*p<0.05; **p <0.01; r represents spearman correlation coefficient).