Figure 1.

MRIs reveal abnormal myelination in children with GRIK2 variants that alter threonine 660 in GluK2

A series of images from MRIs taken at the indicated ages are shown for proband T660K.1. Sagittal images are from T1-weighted pulse sequences; T1 and T2 axial images are shown, and coronal images are T2 weighted. MRIs for other probands are axial images from T1- and T2-weighted scans. Ages where not indicated on the figure are as follows: T660K.2, 10 months; T660K.3, 3 months; T660R.1, 11 months; T660R.2, 6 months. MRI, magnetic resonance imaging.