Figure 3.

rs117132860 genotype is associated with AHR expression in human melanocytes

(A) Expression of the five genes located in the TAD containing rs117132860 in 106 human primary melanocyte cultures as assessed by RNA sequencing (box and whiskers with min. to max.).

(B–D) Rank-normalized gene expression of (B) AHR, (C) TSPAN13, and (D) BZW2 in melanocytes with GG or GA genotype at rs117132860. For violin plots, center lines show the medians, box limits indicate the 25^th and 75^th percentiles, whiskers extend 1.5 times the interquartile range from the 25^th and 75^th percentiles, and all samples are represented by dots. n = 100 (GG) and 6 (GA) sample points.