Table 2.

Decomposition of outer-sphere reorganization free energy in protein and solvent contribution, all values in eV

Hb α chain variants	Mutation	λ	λprot	λsolv	% Contribution of λsolv to λ
Hb	WT	0.69	0.16	0.53	76
Hb M Boston	H58Y	0.69	0.17	0.52	75
α analog of the Hb Zurich β variant	H58R	0.72	0.18	0.54	75
Hb Miyagi	K61E	0.73	0.02	0.71	97
Hb J-Buda	K61N	0.67	0.03	0.64	95
Hb Kirklareli	H58L	0.70	0.19	0.51	73