Table 1.
Binding of TTAPE-Me to the lipid bilayer as a function of the lipid total charge and the charge of headgroup above the phosphate moiety
Lipid type | Monomer binding energy (kJ/mol) | Dimer binding energy (per monomer) (kJ/mol) | Relative binding strength (monomer) | Relative binding strength (dimer) | Lipid total charge | Headgroup charge, excluding phosphate |
---|---|---|---|---|---|---|
CL | −553.7 ± 3.8 | −499.1 ± 3.5 | 1 | 1 | −2 | 0 |
PG | −519.6 ± 0.9 | −476.2 ± 3.7 | 0.94 | 0.95 | −1 | 0 |
PS | −224.9 ± 3.4 | −273.2 ± 3.5 | 0.41 | 0.55 | −1 | 0 (−1/+1) |
PC/PE | −9.5 ± 3.4 | −15.7 ± 1.4 | 0.02 | 0.03 | 0 | +1 |
The mean binding energies and the standard errors are the same as in Fig. 4F. Relative binding strength is computed in comparison to CL.