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. 2021 Jul 18;8(18):2101281. doi: 10.1002/advs.202101281

Figure 8.

Figure 8

Carnosine and PK11195 can alleviate the effects caused by ACR on retinal hyaloid vasculature at 5 dpf. A) Representative confocal images of hyaloid vasculature. White scale bar: 20 µm. B) Quantification of hyaloid vasculature showed significant increasing numbers of branches in akr1a1a1+/+ larvae incubated with 10 µm ACR but rescued by carnosine (dissolved in egg water) and PK11195 (dissolved in DMSO) at 5 dpf, n = 11–18. For statistical analysis one‐way ANOVA followed by Tukey's multiple comparisons test was applied. **< 0.01, ****p < 0.001. NS, not significant. DMSO, dimethylsulfoxide. CAR, carnosine. PK, PK11195.