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. 2021 Jul 15;8(18):2102079. doi: 10.1002/advs.202102079

Figure 5.

Figure 5

The hypothesized pathway indicating propofol promotes tumor metastasis. The hypothesized pathway indicating that propofol activated GABAAR to downregulate TRIM21 and consequently upregulate Src, leading to enhancement of adhesion and extension of the tumor cells with VECs and promotion of tumor metastasis in lungs of mice. Schematic created at BioRender.com with permission.