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. 2021 Jul 29;8(18):2101454. doi: 10.1002/advs.202101454

Figure 2.

Figure 2

A) Chemical Structures of the Disulfide‐Bond‐Bridged PTX‐CIT Prodrugs: α‐PTX‐S‐S‐CIT, β‐PTX‐S‐S‐CIT, and γ‐PTX‐SS‐CIT; B) In vitro redox dual‐responsive drug release of prodrug nanoassemblies in the presence of various concentrations of DTT or H2O2 (n = 3). Reproduced with permission.[ 46 ] Copyright 2018, American Chemical Society. C) Sulfur/selenium/carbon bond‐bridged PTX‐CIT prodrug. D) Images of tumors after in vivo antitumor treatment using different types of prodrug nanoassemblies. Adapted with permission.[ 48 ] Copyright 2019, Nature Publishing Group. E) Result of attempted water dispersion of paclitaxel with a panel of excipients. Reproduced with permission.[ 54 ] Copyright 2018, Nature Publishing Group.