Figure 13.

A) pH/redox responsive polymeric prodrug and fabrication of shell cross‐linked prodrug micelles for antitumor drug transportation. Reproduced with permission.^{[ 192 ]} Copyright 2018, American Chemical Society. B) Illustration of size‐shrinkable and charge‐reversal system for tumor chemo‐immunotherapy in vivo. Reproduced with permission.^{[ 194 ]} Copyright 2020, Elsevier. C) Construction of Boolean logic nanoplatform for combination immunotherapy of cancer. Reproduced with permission.^{[ 195 ]} Copyright 2020, Wiley‐VCH. D) Schematic illustration of the synthesis, upconversion luminescence magnetic resonance imaging, intracellular chemotherapy, and photothermal therapy (PTT) of UCNPs@Au‐DOX nanocomposites. Reproduced with permission.^{[ 196 ]} Copyright 2017, Royal Society of Chemistry. E) Schematic illustration of constructing bifunctional supramolecular prodrug NPs and their application in cancer therapy. Reproduced with permission.^{[ 197 ]} Copyright 2020, Royal Society of Chemistry. F) Schematic illustrations of molecular and supramolecular engineering on tumor‐specific multiple stimuli‐activated dendrimeric nanoassemblies with metabolic blockade and their synergistic effects for overcoming physiological barriers and cellular factors of chemotherapy resistance. Reproduced with permission.^{[ 199 ]} Copyright 2017, American Chemical Society.