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. 2021 Jul 22;8(18):2101619. doi: 10.1002/advs.202101619

Figure 3.

Figure 3

Excellent therapeutic efficacy of HAMs in the mice model with DSS‐induced colitis. a) Experimental design. The mice were provided with sterile water or water containing 3% DSS for 7 days. Oral administration of treatments was given from the second day. All mice were sacrificed two days after DSS drinking stopped. b) Daily changes of body weight were recorded in detail and analyzed, n = 5. c) Everyday disease activity index (DAI) scores were calculated and analyzed, n = 5. d) Macroscopic colon appearance of each group was shown, n = 5 per group. e) Representative macroscopic spleen appearance of each group. f) Representative hematoxylin and eosin (H&E) staining images of colon tissue of each group. Scale bar is 200 µm. g) Colon length was measured and analyzed, n = 5. h) Spleen weight was measured and analyzed, n = 5. i) Colonic damage scores according to H&E staining were analyzed in each group. Significance between every two group was assessed by using Mann–Whitney U‐test; ns, not significant; * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.