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. 2021 Jul 30;144(11):845–858. doi: 10.1161/CIRCULATIONAHA.121.056323

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© 2021 The Authors.

Circulation is published on behalf of the American Heart Association, Inc., by Wolters Kluwer Health, Inc. This is an open access article under the terms of the Creative Commons Attribution Non-Commercial-NoDerivs License, which permits use, distribution, and reproduction in any medium, provided that the original work is properly cited, the use is noncommercial, and no modifications or adaptations are made.

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Figure 1. — Consort flow chart of the EAST-AFNET4 heart failure subanalysis. A total of 798 patients with heart failure were included in this analysis; 396 were randomly assigned to early rhythm control, and 402 were randomly assigned to usual care. During follow-up, in the early rhythm control group 201 of 2049 total follow-up years were lost (147 follow-up years lost because 31 patients withdrew; 54 follow-up years lost because 36 patients were lost to follow-up) and 159 of 2070 total follow-up years were lost in the usual care group (108 follow-up years lost because 26 patients withdrew; 51 follow-up years lost because 33 patients were lost to follow-up). Screening and randomization are replicated from the main article.¹⁴ AF indicates atrial fibrillation; EAST-AFNET4, Early Treatment of Atrial Fibrillation for Stroke Prevention Trial; fu, follow-up; and LVEF, left ventricular ejection fraction.