Figure 2.
Protected T cells have increased canonical markers of tissue residency and include CD4+ regulatory T cells. (A) Subset composition of representative samples using flow cytometry to identify the phenotype on the basis of CCR7 and CD45RA cell-surface expression as TEM (CCR7−CD45RA−), TCM (CCR7+CD45RA−), naive T cells (CCR7+, CD45RA+), and TEMRA (CCR7−CD45RA+) from lung biopsy specimens taken at 6 hours of ex vivo lung perfusion. (B) Compiled data showing paired proportion of TEM for both CD8+ (top) and CD4+ (bottom) T cells