Table 2.
Basal echocardiographic characteristics in SGLT2i and control group
| Variable | SGLT2i (n = 30) | Control (n = 22) | p value |
|---|---|---|---|
| LV end-diastolic diameter (mm) | 46.9 ± 5.0 | 44.5 ± 4.3 | 0.08 |
| LV end-diastolic volume (ml) | 103.3 ± 40.0 | 97.0 ± 25.7 | 0.52 |
| LV indexed end-diastolic volume (ml/m2) | 52.6 ± 18.9 | 50.2 ± 9.7 | 0.59 |
| LV end-systolic volume (ml) | 40.7 ± 26.5 | 33.9 ± 8.5 | 0.19 |
| LV ejection fraction (%) | 62.9 ± 8.2 | 64.6 ± 5.8 | 0.43 |
| LV ejection fraction < 50% | 2 (7%) | 0 (0%) | 0.50 |
| E wave (cm/s) | 72.2 ± 25.5 | 64.2 ± 19.7 | 0.22 |
| A wave (cm/s) | 82.8 ± 18.9 | 87.5 ± 19.2 | 0.41 |
| LA indexed volume (ml/m2) | 31.9 ± 9.8 | 28.7 ± 9.1 | 0.23 |
| Lateral e’ (cm/s) | 8.3 ± 2.2 | 8.3 ± 3.2 | 0.95 |
| Septal e’ (cm/s) | 5.9 ± 1.4 | 5.8 ± 1.2 | 0.73 |
| E/A ratio | 0.83 ± 0.39 | 0.81 ± 0.26 | 0.80 |
| E/e’ ratio | 10.5 ± 3.6 | 9.8 ± 2.4 | 0.40 |
| LV indexed mass (g/m2) | 98.5 ± 27.9 | 90.8 ± 21.0 | 0.28 |
| RWT | 0.47 ± 0.07 | 0.49 ± 0.08 | 0.29 |
| GLS | − 17.8 ± 2.9 | − 19.6 ± 2.5 | 0.02 |
LV left ventricular, LA left atrial, RWT relative wall thickness, GLS global longitudinal strain