Table 1 –
Comparison of clinical factors between subjects with normal versus abnormal sevoflurane induction EEG
| Normal EEG | Abnormal EEG | p value | |
|---|---|---|---|
| (n = 50) | (n = 4) | ||
|
| |||
| Age (months) | 7.5 (4.9, 9.8) | 5.1 (2.0, 10.2) | 0.39 |
| Male gender (no.) | 38 (76%) | 3 (75%) | >0.99 |
| Initial inSEV (%) | 6.7 (6.0, 7.2) | 6.5 (6.2, 7.5) | 0.83 |
| Max etSEV (%) | 6.1 (5.4, 6.6) | 5.9 (5.6, 6.0) | 0.75 |
| EtCO2 min (mmHg) | 16 (11, 20) | 12.5 (9.5, 18) | 0.59 |
| EtCO2 max (mmHg) | 36 (31, 43) | 36.5 (30.5, 42.5) | 0.19 |
| Propofol given (no.) | 17 (34%) | 3 (75%)* | 0.14 |
| Fentanyl given (no.) | 27 (54%) | 1 (25%) | 0.34 |
| Induction time (minutes)♯ | 6 (3, 9) | 5 (4, 8) | 0.74 |
two of three subjects demonstrated IEDs prior to propofol administration
defined as the time beginning from first recorded fraction inspired sevoflurane concentration until any one of the following recorded times – (a) peripheral venous cannula insertion or first recorded intravenous medication administration, (b) anesthesia “ready” indicated by the provider, or (c) securing of the airway (e.g. LMA insertion or endotracheal intubation) – whichever came first.
Wilcoxon Mann-Whitney U test and Fishers Exact test used