Appendix 1—figure 9. Effective potential for TM confinement in a virtual viral membrane.

The flat-bottom region represents the virtual membrane of width ${\displaystyle w_m=5}$ nm, this region allows the TM motif to move freely between the planes $z=\frac{w_m}{2}$ and $z=\frac{-w_m}{2}$, beyond the flat region an energetic penalty is included to restrain the TM to escape the virtual membrane. Energy is measured in reduced energy units.