KU-596 treatment improves sensory function and MNCV in diabetic MQC mice. (A) Mechanical and (B) thermal sensitivity were assessed at the indicated weeks, and the arrow indicates the initiation of daily drug therapy. ND, nondiabetic. Results are mean ± SEM, and number of animals per group is shown in (C). *, p < 0.05 versus time-matched ND mice. #, p < 0.05 versus time-matched STZ + KU-596. (C) MNCV, symbols indicate responses from individual animals, and the results are mean ± SD.