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KU-596 improves sensory function and MNCV in diabetic MQC × Txnip KO mice. (A) Mechanical and (B) thermal sensitivity were assessed at the indicated weeks, and the arrow indicates the initiation of daily drug therapy. Results are mean ± SEM, and number of animals per group is shown in (C). ND, nondiabetic. *, p < 0.05 versus time-matched ND mice; #, p < 0.05 versus time-matched STZ + KU-596. (C) MNCV, symbols indicate responses from individual animals, and the results are mean ± SD.
