. Author manuscript; available in PMC: 2022 Aug 18.

Published in final edited form as: ACS Chem Neurosci. 2021 Aug 3;12(16):3049–3059. doi: 10.1021/acschemneuro.1c00340

Table 1.

Effect of STZ and KU-596 on Weight, FBG, and HbA1c in MQC and MQC × Hsp70 KO Mice^a

genotype	treatment	initial weight (g)	final weight (g)	final FBG (mg/dL)	HbA1c (%)
MQC	nondiabetic (7)	19.6 ± 1.1	27.0 ± 1.7	154 ± 7	nd
	nondiabetic + KU-596 (8)	19.0 ± 0.7	26.3 ± 1.4	142 ± 10^{^}	nd
	diabetic (15)	19.6 ± 0.7	25.2 ± 1.0	261 ± 9^*	nd
	diabetic + KU-596 (13)	19.7 ± 0.6	24.9 ± 1.0	179 ± 9^#	nd
MQC × Hsp70 KO	nondiabetic (9)	20.3 ± 1.3	26.6 ± 1.8	135 ± 5	4.4 ± 0.2
	nondiabetic + KU-596 (5)	20.0 ± 1.3	25.4 ± 2.5	134 ± 11	nd
	diabetic (10)	21.1 ± 1.3	24.5 ± 1.2	311 ± 32^*	8.1 ± 1.4^*
	diabetic + KU-596 (11)	20.4 ± 1.4	24.8 ± 1.2	345 ± 38^*	7.2 ± 1.1^*

Animal number is indicated in parentheses.

, p < 0.05 vs nondiabetic,

^{^}

, p < 0.05 versus nondiabetic,

, p < 0.05 versus diabetic.

nd, not determined.