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. Author manuscript; available in PMC: 2022 Aug 18.
Published in final edited form as: ACS Chem Neurosci. 2021 Aug 3;12(16):3049–3059. doi: 10.1021/acschemneuro.1c00340

Table 2.

Effect of STZ and KU-596 on Weight, FBG, and HbA1c in MQC × Txnip KO Micea

treatment final weight (g) final FBG (mg/dL) HbA1c (%)
nondiabetic + vehicle (11) 29.3 ± 1.1  124 ± 8 4.5 ± 0.3
nondiabetic + KU-596 (10) 29.1 ± 1.4  130 ± 5 4.2 ± 0.1
diabetic + vehicle (16) 26.7 ± 0.8  284 ± 24* 7.3 ± 2.1
diabetic + KU-596 (17) 26.8 ± 0.8  242 ± 33* 8.3 ± 0.9*
a

Animal number is indicated in parentheses.

*

, p < 0.05 vs nondiabetic.