TABLE 1.
Comparison of baseline characteristics between ACLD patients and those with vascular liver disease only
| Characteristics | Overall, n = 133 | ACLD, n = 104 | Vascular liver disease, n = 29a | P value |
|---|---|---|---|---|
| Age, y, mean ± SD | 58.1 ± 14.1 | 59.5 ± 13.3 | 53.0 ± 15.7 | .027 |
| Male sex, n (%) | 79 (59.4%) | 59 (56.7%) | 20 (69.0%) | .235 |
| BMI, kg/m2, mean ± SD | 27.0 ± 5.3 | 27.5 ± 5.4 | 25.1 ± 4.4 | .033 |
| Platelets, G/L | 123 (91‐193) | 116 (87‐176) | 217 (129‐296) | <.001 |
| Albumin, g/dL | 37.9 ± 6.0 | 36.9 ± 6.0 | 40.8 ± 5.1 | .002 |
| Etiology of liver disease, n (%) | ||||
| ALD | 25 (18.8%) | 25 (24.0%) | — | — |
| NAFLD | 25 (18.8%) | 25 (24.0%) | — | |
| Viral hepatitis | 13 (9.8%) | 13 (12.5%) | — | |
| Others | 33 (24.8%) | 32 (30.7%) | 1 (3.4%) | |
| BCS | 9 (6.8%) | 9 (8.7%) | — | |
| PSVD | 10 (7.5%) | — | 10 (34.5%) | |
| PVT without evidence of ACLD | 18 (13.5%) | — | 18 (62.1%) | |
| Clinical characterization of liver disease | ||||
| HCC | 33 (24.8%) | 33 (31.7%) | 0 (0.0%) | <.001 |
| BCLC 0/A | 10 (7.5%) | 10 (9.6%) | 0 (0.0%) | .007 |
| BCLC B | 9 (6.8%) | 9 (8.7%) | 0 (0.0%) | |
| BCLC C/D | 14 (10.5%) | 14 (13.5%) | 0 (0.0%) | |
| Malignancy other than HCC | 11 (8.3%) | 6 (5.8%) | 5 (17.2%) | .061 |
| Decompensated liver disease | 66 (49.6%) | 55 (52.9%) | 11 (37.9%) | .154 |
| Ascites | 57 (42.9%) | 47 (45.2%) | 10 (34.5%) | .303 |
| Hepatic encephalopathy | 22 (16.5%) | 20 (19.2%) | 2 (6.9%) | .159 |
| Varices | 85 (63.9%) | 70 (67.3%) | 15 (51.7%) | .122 |
| Small | 58 (43.6%) | 52 (50.0%) | 6 (20.7%) | .017 |
| Large | 27 (20.3%) | 18 (17.3%) | 9 (31.0%) | |
| PVT | 102 (76.7%) | 77 (74.0%) | 25 (86.2%) | .171 |
| History of variceal bleeding | 14 (10.5%) | 13 (12.5%) | 1 (3.4%) | .302 |
| Portal hypertensive gastropathy | 41 (30.8%) | 37 (35.6%) | 4 (13.8%) | .068 |
| Splenomegaly | 87 (65.4%) | 71 (68.3%) | 16 (55.2%) | .190 |
| History of TIPS | 9 (6.8%) | 7 (6.7%) | 2 (6.9%) | 1.000 |
| Severity of liver disease | ||||
| Child‐Pugh Score, points | 6 (5‐8) | 6 (5‐8) | 5 (5‐6) | .001 |
| A | 78 (58.6%) | 53 (51.0%) | 25 (86.2%) | .003 |
| B | 47 (35.3%) | 44 (42.3%) | 3 (10.3%) | |
| C | 8 (6.0%) | 7 (6.7%) | 1 (3.4%) | |
| UNOS MELD, points | 11.1 ± 4.1 | 11.7 ± 4.2 | 8.9 ± 2.7 | <.001 |
Abbreviations: ALD, alcoholic liver disease; BCLC, Barcelona Clinic Liver Cancer; BCS, Budd‐Chiari syndrome; BMI, body mass index; HCC, hepatocellular carcinoma; MELD, model for end‐stage liver disease; NALFD, non‐alcoholic fatty liver disease; PSVD, porto‐sinusoidal vascular disease; PVT, portal vein thrombosis; SD, standard deviation; TIPS, transjugular intrahepatic portosystemic shunt.
a
Including patients with PSVD, PVT without parenchymal liver disease and veno‐occlusive disease.
Bold values indicate significance (P ≤ .05)